Tutkimusta akupunktion käytöstä erilaisissa sydän- ja verisuonisairauksissa sekä metabolisissa ongelmissa

Akupunktiota löytyy tutkimusta sydän- ja verisuonitautien tukihoidossa sekä erilaisten metabolisten sairauksien suhteen.

Joissain tutkimuksissa ollaan havaittu, että tavanomaisen hoidon tukena akupunktion saattaa vähentää sydänoireita esimerkiksi vakaan angina pectoris -kivun yhteydessä. Myös joidenkin muiden sydänoireistojen tukihoitona akupunktiota ollaan tutkittu.

Akupunktiosta on tehty myös tutkimuksia metabolisen oireyhtymän hoidossa, sen vaikutuksista rasva-aineenvaihduntaan sekä esimerkiksi diabeetikoiden silmäongelmien suhteen.

Vakavien sydän- ja verisuonisairauksien kohdalla akupunktiota käytetään vain tukihoitona lääkärin määräämän hoidon ohella.

 
 

Selaa tutkimuksia tai valitse aiheaulue




 
 

Study of Latest Trend on Acupuncture for Obesity Treatment.

"...Results: Most studies were conducted in animals, followed by case reports and clinical trials. In animal researches and case reports, pharmacopuncture was the most used intervention. In case studies, electroacupuncture, thread-embedding therapy, manual acupuncture, acupotomy, and auricular acupuncture were also used. In animal researches, pharmacopuncture treatment was associated with improvement in obesity indices. In the case of local obesity, specific acupuncture techniques such as thread-embedding therapy and pharmacopuncture were associated with significant improvements in local obesity, even when diet and exercise were not controlled for. ..."
Chun H., Kim D. et al. (2021) Study of Latest Trend on Acupuncture for Obesity Treatment. J Pharmacopuncture. 2021;24(4):173-181.   🔗

Acupuncture for treating chronic stable angina pectoris associated anxiety and depression: A systematic review and meta-analysis.

"...RESULTS: Seven trials involving 893 subjects were included. Meta-analysis results showed that acupuncture combined with standard care was more effective in relieving anxiety and depression, reducing angina attack frequency, and angina pain intensity than sham acupuncture with standard care and standard care alone. In addition, the effect remained until 16 weeks after acupuncture. The safety of acupuncture for CSAP-associated anxiety and depression was also high. Nonetheless, the quality of evidence ranged from low to moderate. ..."
Tu M., Jiang Y. et al. (2021) Acupuncture for treating chronic stable angina pectoris associated anxiety and depression: A systematic review and meta-analysis. Complement Ther Clin Pract. 2021;45:101484.  🔗

Roles of central orexinergic system on cardiovascular function and acupuncture on intervention of cardiovascular risk: Orexinergic system mediate the role of acupuncture?

"Central orexinergic system contributes to the regulation of cardiovascular function. Orexinergic neurons receiving projections of nerve fibers from multiple structures of brain which involved in control and regulation of cardiovascular function locate in hypothalamus, and their axon terminals widely project to various central structures where orexins receptors are expressed. Here, we summarize the present ..."
Gao H., Wu Z. et al. (2021) Roles of central orexinergic system on cardiovascular function and acupuncture on intervention of cardiovascular risk: Orexinergic system mediate the role of acupuncture? Neuropeptides. 2021;87:102132.  🔗

Acupuncture for Hypertension in Animal Models: A Systematic Review and Meta-Analysis.

"...Results: 67 studies containing 1522 animals were included. According to the ARRIVE guideline, 8 items were assessed as poor and 4 items were assessed as excellent. According to the SYRCLE tool, all studies were judged as having high risk of bias. Compared with the hypertension group, the pooled results showed significant antihypertension effects of acupuncture for SBP, DBP, and MAP. Similarly, compared with the sham-acupuncture group, the pooled results showed significant antihypertension effects of acupuncture for SBP, DBP, and MAP. ..."
Xiao L., Li Z. et al. (2021) Acupuncture for Hypertension in Animal Models: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med. 2021:8171636.  🔗

Mechanism of Action of Acupuncture in Obesity: A Perspective From the Hypothalamus.

"Obesity is a prevalent metabolic disease caused by an imbalance in food intake and energy expenditure. Although acupuncture is widely used in the treatment of obesity in a clinical setting, its mechanism has not been adequately elucidated. As the key pivot of appetite signals, the hypothalamus receives afferent and efferent signals from the brainstem ..."
Wang L., Yu C. et al. (2021) Mechanism of Action of Acupuncture in Obesity: A Perspective From the Hypothalamus. Front Endocrinol (Lausanne). 2021;12:632324.  🔗

The Effect of Acupuncture on Glucose Metabolism and Lipid Profiles in Patients with PCOS: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

"Objective To evaluate the effectiveness of acupuncture on glucose metabolism and lipid profiles in patients with polycystic ovary syndrome (PCOS). Methods Databases, including the China National Knowledge Infrastructure (CNKI), the China Science and Technology Journal Database (VIP), Wanfang, PubMed, and the Cochrane Library were searched for the relevant literature, with the retrieval deadline being ..."
Zheng R., Qing P. et al. (2021) The Effect of Acupuncture on Glucose Metabolism and Lipid Profiles in Patients with PCOS: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Evid Based Complement Alternat Med. 2021.  🔗

Acupuncture for Regulating Blood Pressure of Stroke Patients: A Systematic Review and Meta-Analysis.

"Blood pressure (BP) after a stroke is affected by autonomic regulation, the Cushing reaction, and basal history of hypertensive, arteriosclerotic conditions. To prevent recurrent stroke attack and its complications, BP must be regulated to within the normal range through monitoring, rest, and medication. Previous studies have reported that acupuncture may be effective in lowering ..."
Hong S., Ahn L. et al. (2020) Acupuncture for Regulating Blood Pressure of Stroke Patients: A Systematic Review and Meta-Analysis. J Altern Complement Med. 2020;26(12):1105-1116.   🔗

Acupuncture for metabolic syndrome: systematic review and meta-analysis.

"...RESULTS: A total of 13 RCTs were identified with 423 subjects undergoing acupuncture regimens and 411 receiving control interventions. Active acupuncture yielded better outcomes than sham acupuncture with respect to improving multiple MetS indices. Acupuncture monotherapy had similar effectiveness in controlling triglyceride levels and high-density lipoprotein levels compared to CMs. The overall effects of adjunctive acupuncture were markedly greater than those of controls (CMs + LI, CMs, and LI) with respect to waist circumference with a mean difference of -5.11 cm (Z = 4.57, p < 0.001) and body mass index with a mean difference of -2.54 (Z = 5.38, p <0.001), and improvements were observed in most hyperlipidemia indices and fasting blood glucose. An evidence-based acupuncture regimen was identified as a future treatment strategy for MetS. ..."
Li X., Jia H. et al. (2020) Acupuncture for metabolic syndrome: systematic review and meta-analysis. Acupunct Med. 2020:964528420960485.  🔗

Acupuncture and related techniques for obesity and cardiovascular risk factors: a systematic review and meta-regression analysis.

"...RESULTS: Thirty-three RCTs were included (n=2503 patients). Compared with non-acupuncture interventions, acupuncture produced a greater reduction in body weight (WMD -1.76 kg, 95% CI -2.22 to -1.30, I=77%; moderate quality), body mass index (WMD -1.13 kg/m, 95% CI -1.38 to -0.88, I=85%; low quality) and waist circumference (WMD -2.42 cm, 95% CI -3.22 to -1.62, I=75%; moderate quality). Acupuncture plus lifestyle intervention resulted in a greater reduction in body weight than acupuncture alone (MD -1.94 kg, 95% CI -3.17 to -0.70). Acupuncture also led to a greater reduction in total cholesterol (WMD -12.87 mg/dL, 95% CI -22.17 to -3.57, I=87%; very low quality) and low-density lipoprotein cholesterol (WMD -13.52 mg/dL, 95% CI -21.47 to -5.58, I=74%; low quality). The differences were not statistically significant for blood glucose or blood pressure. ..."
Chen J., Chen D. et al. (2020) Acupuncture and related techniques for obesity and cardiovascular risk factors: a systematic review and meta-regression analysis. Acupunct Med. 2020;38(4):227-234.   🔗

Acupuncture for treating diabetic retinopathy: A systematic review and meta-analysis of randomized controlled trials.

"...RESULTS: Of 864 citations, 6 RCTs met the inclusion criteria of our review. Four studies reported the beneficial effects of acupuncture with standard medication or acupuncture alone compared with standard medication or no treatment on the effective rate. Only three studies showed that acupuncture combined with standard medications significantly improved visual acuity compared to standard medication alone. None of the studies reported on adverse events. The risk of bias of the included studies was judged to be of "some concern" and was marked with a moderate and low certainty of evidence in different outcomes. ..."
Ang L., Song E. et al. (2020) Acupuncture for treating diabetic retinopathy: A systematic review and meta-analysis of randomized controlled trials. Complement Ther Med. 2020;52:102490.  🔗

Acupuncture versus sham acupuncture for simple obesity: a systematic review and meta-analysis.

"Obesity is a growing chronic health problem worldwide. Studies about acupuncture for obesity treatment are many. But there are some doubts about the effectiveness of acupuncture versus sham acupuncture in treating obesity due to its lack of medical evidence. Therefore, the aim of this study is to assess the efficacy of acupuncture for obesity ..."
Zhong Y., Luo X. et al. (2020) Acupuncture versus sham acupuncture for simple obesity: a systematic review and meta-analysis. Postgrad Med J. 2020;96(1134):221-227.   🔗

Effects of auriculotherapy on weight and body mass index reduction in patients with overweight or obesity: Systematic review and meta-analysis.

"...RESULTS: The results revealed an association between auriculotherapy and weight reduction (WMD, 1.507; 95% CI, 0.606-2.407; p < 0.000). Auriculotherapy was also significantly associated with BMI reduction (WMD, 0.865; 95% CI, 0.533-1.196; p < 0.004). ..."
Mendonça C., Coelho Dos Santos L. et al. (2020) Effects of auriculotherapy on weight and body mass index reduction in patients with overweight or obesity: Systematic review and meta-analysis. Complement Ther Clin Pract. 2020;38:101069.  🔗

Traditional Chinese medicine foot bath combined with acupoint massage for the treatment of diabetic peripheral neuropathy: A systematic review and meta-analysis of 31 RCTs.

"In this study, we aim to evaluate the efficiency and safety of traditional Chinese medicine foot bath combined with acupoint massage for the treatment of diabetic peripheral neuropathy. A total of eight online databases were searched to collect studies published up to February 2019. Study quality of each included article was evaluated by the Cochrane ..."
Fu Q., Yang H. et al. (2020) Traditional Chinese medicine foot bath combined with acupoint massage for the treatment of diabetic peripheral neuropathy: A systematic review and meta-analysis of 31 RCTs. Diabetes Metab Res Rev. 2020;36(2):e3218.   🔗

The effect of auricular therapy on blood pressure: A systematic review and meta-analysis.

"...RESULTS: We systematically reviewed 44 randomized controlled trials (involving 5022 patients through June 2018). Auricular acupressure plus antihypertensive drugs might be more effective than antihypertensive drugs alone in both reducing systolic blood pressure value after treatment (=464 patients; mean difference, -5.06 mm Hg; 95% confidence interval, -6.76- -3.36, <0.00001; =32%), decreasing diastolic blood pressure after treatment (=464 patients; mean difference, -5.30 mm Hg; 95% confidence interval, -6.27- -4.33, <0.00001; =0%) and the efficacy rate (relative risk, 1.22; 95% confidence interval, 1.17-1.26; <0.00001; =0%). ..."
Gao J., Chen G. et al. (2020) The effect of auricular therapy on blood pressure: A systematic review and meta-analysis. Eur J Cardiovasc Nurs. 2020;19(1):20-30.   🔗

Role of acupuncture in the treatment of insulin resistance: A systematic review and meta-analysis.

"...RESULTS: With acupuncture, the homeostasis model assessment of insulin resistance (homa-IR) significantly decreased (mean difference (MD) = -1.04, 95% confidence interval (CI) -1.37 to -0.71; P < 0.00001), as did fasting blood glucose (FBG) (MD = -0.56, 95% CI -0.88 to -0.25; P = 0.0005), 2 h postprandial blood glucose (2hPG) (MD = -0.91, 95% CI -1.62 to -0.20; P = 0.01), and fasting insulin (FINS) (MD = -3.23, 95% CI -4.14 to -2; P < 0.00001). Meanwhile, the insulin sensitivity index (ISI) (MD = 0.36, 95% CI 0.18 to 0.53; P < 0.0001) increased, and fewer adverse events occurred. ..."
Wu L., Chen X. et al. (2019) Role of acupuncture in the treatment of insulin resistance: A systematic review and meta-analysis. Complement Ther Clin Pract. 2019;37:11-22.  🔗

The efficacy of acupuncture for stable angina pectoris: A systematic review and meta-analysis.

"...RESULTS: Pooled analysis of 17 eligible trials with 1516 participants showed that acupuncture was associated with reduced angina attack frequency (-4.91; 95% confidence interval, -6.01- -3.82;  < 0.00001) and improved depression (-1.23; 95% confidence interval, -1.47- -1.00;  < 0.00001) and anxiety level (-0.96; 95% confidence interval, -1.16- -0.75;  < 0.00001) relative to sham treatment or standard care alone. No increased risk of adverse events was observed during treatment (relative risk, 0.70; 95% confidence interval, 0.33-1.48;  = 0.35). No significant improvement was shown in nitroglycerin use or angina intensity. The included studies were associated with unclear to high risk of selection or performance bias, and the quality of evidence was low to moderate. ..."
Yang M., Sun M. et al. (2019) The efficacy of acupuncture for stable angina pectoris: A systematic review and meta-analysis. Eur J Prev Cardiol. 2019:2047487319876761.  🔗

Meta-Analysis of Electroacupuncture in Cardiac Anesthesia and Intensive Care.

"...RESULTS: The initial search yielded 477 citations, but only 7 prospective RCTs enrolling a total of 321 patients were included. The use of GA + EA reduced the dosage of intraoperative anesthetic drugs ( < .05), leading to shorter MV time ( < .01) and ICU stay ( < .05) as well as reduced postoperative dose of vasoactive drugs ( < .001). In addition, significantly lower levels of troponin I ( < .01) and tumor necrosis factor α ( < .01) were observed. ..."
Asmussen S., Przkora R. et al. (2019) Meta-Analysis of Electroacupuncture in Cardiac Anesthesia and Intensive Care. J Intensive Care Med. 2019;34(8):652-661.   🔗

Acupuncture for type 2 diabetes mellitus: A systematic review and meta-analysis of randomized controlled trials.

"...RESULTS: A total of 21 studies, which comprised a total of 1943 participants, were included in the final meta-analysis. Compared with sham acupuncture or no acupuncture plus baseline treatments, acupuncture plus baseline treatments yield reduction in FBG(MD 1.21 mmol/l, 95%CI 1.56 to 0.87), 2 h BG(MD 2.13 mmol/l, 95%CI 2.79 to 1.46), HA1c (MD 1.12%, 95%CI 1.62 to 0.62). Our results also show acupuncture can improve blood lipids and blood pressure control, and reduce weight. ..."
Chen C., Liu J. et al. (2019) Acupuncture for type 2 diabetes mellitus: A systematic review and meta-analysis of randomized controlled trials. Complement Ther Clin Pract. 2019;36:100-112.  🔗

The effects of Chinese herbal medicines for treating diabetic foot ulcers: A systematic review of 49 randomized controlled trials.

"...RESULTS: Forty-nine RCTs, all conducted in China, involving 3646 participants were included. Most of the included trials had unclear or high risk of bias. Twenty-six trials could be pooled in five Meta-analyses, the remaining trials could not be pooled due to the obvious clinical heterogeneity. Only low evidence showed CHM therapy may have 42%-60.4% participants healed completely after treatment, approximately twice (RR 1.42-1.76) as much as the healed rates in conventional therapy (or plus hot water foot bath) group. Majority of the included trials reported benefit of CHM group on shortening healing time (4-23 days) and reducing ulcer wound size (at least 2 cm). No serious adverse events were reported related to the medication in all trials. ..."
Wang Y., Cao H. et al. (2019) The effects of Chinese herbal medicines for treating diabetic foot ulcers: A systematic review of 49 randomized controlled trials. Complement Ther Med. 2019;44:32-43.  🔗

Acupuncture for the Treatment of Cardiovascular Diseases: A Systematic Review.

"Acupuncture, for the westerns countries, is an innovative and low-cost therapy for treatment and prevention of cardiovascular diseases (CVDs). However, most of its effects and mechanisms are poorly understood. Thus, the objective of this work was to systematically review the literature regarding the clinical effects of acupuncture for the treatment and prevention of CVDs. ..."
de Lima Pimentel R., Duque A. et al. (2019) Acupuncture for the Treatment of Cardiovascular Diseases: A Systematic Review. J Acupunct Meridian Stud. 2019;12(2):43-51.   🔗

Acupuncture as an Adjunctive Treatment for Angina Due to Coronary Artery Disease: A Meta-Analysis.

"BACKGROUND In traditional Chinese medicine, acupuncture has been used to treat angina due to coronary artery disease (CAD). The aim of this systematic review of the literature and meta-analysis was to identify published randomized controlled trials (RCTs) that quantified the effectiveness of adjunctive acupuncture treatment in patients with angina due to CAD who were ..."
Huang X., Guo S. et al. (2019) Acupuncture as an Adjunctive Treatment for Angina Due to Coronary Artery Disease: A Meta-Analysis. Med Sci Monit. 2019;25:1263-1274.  🔗

Acupuncture therapy for the treatment of stable angina pectoris: An updated meta-analysis of randomized controlled trials.

"...RESULTS: A total of 12 RCTs involving 974 patients were enrolled in this study. The pooled results showed that both acupuncture group (RR: 0.35, P < 0.00001; RR: 0.49, P < 0.00001) and acupuncture plus medicine group (RR: 0.26, P < 0.00001; RR: 0.52, P = 0.03) were associated with a higher percentage of improved anginal symptoms as well as electrocardiographic (ECG) results compared to medicine group. The acupuncture plus medicine group also had a lower intake rate of nitroglycerin than medicine group (Non-event RR: 0.79, P = 0.03). However, there was no significant difference in the reduction or discontinuation of nitroglycerin intake between acupuncture group and medicine group. No acupuncture-related adverse effects were observed or reported in the included trials. ..."
Liu Y., Meng H. et al. (2019) Acupuncture therapy for the treatment of stable angina pectoris: An updated meta-analysis of randomized controlled trials. Complement Ther Clin Pract. 2019;34:247-253.  🔗

Acupuncture for the treatment of lower limb diabetic peripheral neuropathy: a systematic review.

"...RESULTS: Ten studies with 432 participants were included: three randomised controlled trials (RCTs), two pilot RCTs, three uncontrolled clinical trials, one quasi-RCT and one prospective case series. Improvements in DPN pain symptoms were reported by all studies. Heterogeneity of outcome measures prevented a meta-analysis. Variations were found in needle retention time and point selection, as well as total number and frequency of treatments. Common acupuncture point selections were ST36 and SP6. Half of the studies used local point selection. Studies conducted outside China had better acupuncture reporting and quality according to the STRICTA checklist and NICMAN scales, respectively. Risk of bias was high or unclear in the majority of studies for all domains except attrition bias. ..."
Nash J., Armour M. et al. (2019) Acupuncture for the treatment of lower limb diabetic peripheral neuropathy: a systematic review. Acupunct Med. 2019;37(1):3-15.   🔗

The Effectiveness of Acupoint Catgut Embedding Therapy for Abdominal Obesity: A Systematic Review and Meta-Analysis.

"Acupoint catgut embedding is a useful therapy for weight management and widely applied in China. This review aimed to systematically evaluate the effects of acupoint catgut embedding on abdominal obesity. We searched the PubMed, Cochrane-Library, Embase, OVID, MEDLINE, ISI (web of science), Wanfang, VIP, CBM, and CNKI for randomized controlled trials that used acupoint ..."
Sheng J., Jin X. et al. (2019) The Effectiveness of Acupoint Catgut Embedding Therapy for Abdominal Obesity: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med. 2019:9714313.  🔗

The Effect of Acupuncture and Moxibustion on Heart Function in Heart Failure Patients: A Systematic Review and Meta-Analysis.

"...Results: Thirty-two RCTs involving 2499 patients were included. Most studies had an unclear risk regarding blinding and allocation concealment. Compared with the traditional treatment group, the experimental group had a higher efficacy rate (odds ratio (OR) = 2.61, 95% confidence interval (95%CI): = [1.84; 3.72],  = 0%, < 0.0001) and a significantly improved left ventricular ejection fraction (LVEF) (mean difference (MD) = 6.34, 95%CI = [4.11, 8.57],  = 93%, < 0.0001), cardiac output (CO) (MD = 1.02, 95%CI = [0.65, 1.39],  = 94%, < 0.0001), 6-minute walk test (6MWT) (MD = 43.6, 95%CI = [37.43, 49.77],  = 0%, < 0.0001), and reduced brain-type natriuretic peptide (BNP) (MD = -227.99, 95%CI = [-337.30, -118.68], I = 96%, < 0.0001). Adverse events were inadequately reported in most studies. ..."
Liang B., Yan C. et al. (2019) The Effect of Acupuncture and Moxibustion on Heart Function in Heart Failure Patients: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med. 2019:6074967.  🔗

Effectiveness of Acupuncture in Treatment of Simple Obesity in Animal Models: A Systematic Review and Meta-Analysis.

"...Results: A total of 108 trials involving 5731 rats were included. Meta-analysis showed that acupuncture had better effect on reducing weight (SMD -2.60, 95%CI: -2.93 to -2.26, p<0.00001) and Lee's index (SMD -2.62, 95%CI:-3.18 to -2.06, p<0.00001) compared with control group. However, the methodological quality of included studies was generally poor. Details of blinding were not reported in most studies. In spite of high heterogeneity being observed on the merged data, sensitivity analysis using the leave-one-out approach, subgroup analysis based on different acupuncture techniques, and rat strains and meta-regression all failed to find the sources of heterogeneity. The asymmetric funnel plot suggested publication bias. Besides, adverse events were not reported in any reports. ..."
Fan X., Yu M. et al. (2019) Effectiveness of Acupuncture in Treatment of Simple Obesity in Animal Models: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med. 2019:5459326.  🔗

Is Acupuncture Effective for Improving Insulin Resistance? A Systematic Review and Meta-analysis.

"This study aimed to evaluate the clinical efficacy of acupuncture for intervening insulin resistance (IR) by meta-analysis of related randomized controlled trials (RCTs). Studies published prior to 31 January 2018 were searched on Pubmed, Medline, Cochrane Library, Embase databases and Chinese databases. Only RCTs, which examined acupuncture as the sole or adjunctive treatment for IR-related diseases, ..."
Song A., Zhang Y. et al. (2018) Is Acupuncture Effective for Improving Insulin Resistance? A Systematic Review and Meta-analysis. Curr Med Sci. 2018;38(6):1109-1116.   🔗

Acupuncture for hypertension.

"...RESULTS: Twenty-two RCTs (1744 people) met our inclusion criteria. The RCTs were of variable methodological quality (most at high risk of bias because of lack of blinding). There was no evidence for a sustained BP lowering effect of acupuncture; only one trial investigated a sustained effect and found no BP lowering effect at three and six months after acupuncture. Four sham acupuncture controlled trials provided very low quality evidence that acupuncture had a short-term (one to 24 hours) effect on SBP (change) -3.4 mmHg (-6.0 to -0.9) and DBP -1.9 mmHg (95% CI -3.6 to -0.3). Pooled analysis of eight trials comparing acupuncture with angiotensin-converting enzyme inhibitors and seven trials comparing acupuncture to calcium antagonists suggested that acupuncture lowered short-term BP better than the antihypertensive drugs. However, because of the very high risk of bias in these trials, we think that this is most likely a reflection of bias and not a true effect. As a result, we did not report these results in the 'Summary of findings' table. Safety of acupuncture could not be assessed as only eight trials reported adverse events. AUTHORS' ..."
Yang J., Chen J. et al. (2018) Acupuncture for hypertension. Cochrane Database Syst Rev. 2018;11:CD008821.  🔗

Effects of acupuncture on vascular dementia (VD) animal models: a systematic review and meta-analysis.

"...RESULTS: Sixteen studies involving 363 animals met the inclusion criteria. The included studies scored between 4 and 8 points, and the mean was 5.44. The results of the meta-analysis indicated remarkable differences with acupuncture on increasing the duration in the former platform quadrant both in EO models (SMD = 1.56, 95% CI: 1.02 ~ 2.11; p < 0.00001) and 2-VO models (SMD 4.29, 95% CI 3.23 ~ 5.35; p < 0.00001) compared with the control groups. ..."
Zhang Z., Liu Z. et al. (2018) Effects of acupuncture on vascular dementia (VD) animal models: a systematic review and meta-analysis. BMC Complement Altern Med. 2018;18(1):302.   🔗

Conventional Acupuncture for Cardiac Arrhythmia: A Systematic Review of Randomized Controlled Trials.

"...RESULTS: Nine qualified studies involving 638 patients were included. Only 1 study had definitely low risk of bias, while 7 trials were rated as unclear and 1 as high. Meta-analysis of CA alone did not have a significant benefit on response rate compared to amiodarone in patients with atrial fibrillation (Af) and atrial flutter (AF) [relative risk (RR): 1.09; 95% confidence interval (CI): 0.79-1.49; P=0.61; I=61%, P=0.11]. However, 1 study with higher methodological quality detected a lower recurrence rate of Af in CA alone as compared with sham acupuncture plus no treatment, and benefits on ventricular rate and time of conversion to normal sinus rhythm were found in CA alone group by 1 study, as well as the response rate in CA plus deslanoside group by another study. Meta-analysis of CA plus anti-arrhythmia drug (AAD) was associated with a significant benefit on the response rate when compared with AAD alone in ventricular premature beat (VPB) patients (RR, 1.19, 95% CI: 1.05-1.34; P=0.005; I=13%, P=0.32), and an improvement in quality-of-life score (QOLS) of VPB also showed in 1 individual study. Besides, a lower heart rate was detected in the CA alone group by 1 individual study when compared with no treatment in sinus tachycardia patients (MD-21.84 [-27.21,-16.47]) and lower adverse events of CA alone were reported than amiodarone. ..."
Liu J., Li S. et al. (2018) Conventional Acupuncture for Cardiac Arrhythmia: A Systematic Review of Randomized Controlled Trials. Chin J Integr Med. 2018;24(3):218-226.   🔗

Acupuncture safety in patients receiving anticoagulants: a systematic review.

"...RESULTS: Of 39 potentially relevant citations, 11 met inclusion criteria: 2 randomized trials, 4 case series, and 5 case reports. Seven provided reporting quality sufficient to assess acupuncture safety in 384 anticoagulated patients (3974 treatments). Minor-moderate bleeding related to acupuncture in an anticoagulated patient occurred in one case: a large hip hematoma, managed with vitamin K reversal and warfarin discontinuation following reevaluation of its medical justification. Blood-spot bleeding, typical for any needling/injection and controlled with pressure/cotton, occurred in 51 (14.6%) of 350 treatments among a case series of 229 patients. Bleeding deemed unrelated to acupuncture during anticoagulation, and more likely resulting from inappropriately deep needling damaging tissue or from complex anticoagulation regimens, occurred in 5 patients. No bleeding was reported in 2 studies (74 anticoagulated patients): 1 case report and 1 randomized trial prospectively monitoring acupuncture-associated bleeding as an explicit end point. Altogether, 1 moderate bleeding event occurred in 3974 treatments (0.003%). ..."
Mcculloch M., Nachat A. et al. (2015) Acupuncture safety in patients receiving anticoagulants: a systematic review. Perm J. 2015;19(1):68-73.   🔗