Tutkimusta ruuansulatuselimistön ja suoliston ongelmiin liittyen

Akupunktiota on tutkittu paljon erilaisten ruuansulatusongelmien ja suoliston toiminnallisten häiriöiden hoidossa. Oheisissa tutkimuksissa akupunktiolla on todettu olevan vaikutusta mm. joihinkin suolistovaivoihin, kuten vatsakipuihin, turvotuksiin, ripuleihin sekä ummetukseen.

Lievien toiminnallisten oireiden suhteen akupunktiota voidaan käyttää yksinään, mutta vakavampien suoliston ongelmien, kuten suolistosyöpien ja tulehduksellisten suolistosairauksien yhteydessä akupunktiota käytetään ja tutkitaan tukihoitona muille lääketieteellisille hoidoille.

Suomessa akupunktiosta haetaan usein apua erilaisiin ruuansulatukseen ja suolistoon liittyviin ongelmiin, joille ei ole löytynyt lääketieteellistä diagnoosia tai joiden hoitoon tarkoitetuista lääkkeistä on ole ollut tarpeeksi apua. Välillä apua haetaan myös lääkkeiden aiheuttamiin sivuvaikutuksiin.

 
 

Selaa tutkimuksia tai valitse aiheaulue




 
 

Effectiveness and safety of acupuncture for treating functional constipation: An overview of systematic reviews.

"...RESULTS: Thirteen SRs that examined the clinical utility of acupuncture for treating FC were identified. Using the AMSTAR 2 tool, we rated 92.3% (12/13) of the SRs as "critically low" confidence and one study as "low" confidence. Using the ROBIS criteria, 38.5% (5/13) of the SRs were considered to have "low risk" of bias. Based on PRISMA-A, 76.9% (10/13) of the SRs had over 70% compliance with reporting standards. The inter-rater agreement was good for AMSTAR 2, ROBIS, and PRISMA-A. Using the GRADE tool, we classified 22.5% (9/40) of the measured outcomes as "moderate" quality, 57.5% (23/40) as "low" quality, and 20.0% (8/40) as "very low" quality. The inter-rater agreement was moderate when using GRADE. Descriptive analyses indicated that acupuncture was more efficacious than sham acupuncture for improving weekly complete spontaneous bowel movements (CSBMs) and for raising the Bristol Stool Form Scale (BSFS) score. Acupuncture appeared to be superior to anti-constipation drugs for improving weekly spontaneous bowel movements, the total effective rate, and the Patient Assessment of Constipation Quality of Life score. Although ten SRs mentioned the occurrence of adverse events, serious adverse events were not associated with acupuncture treatment. ..."
Yao J., Chen L. et al. (2021) Effectiveness and safety of acupuncture for treating functional constipation: An overview of systematic reviews. J Integr Med. 2021.  🔗

Evaluating traditional Chinese medicine diagnostic instruments for functional dyspepsia: systematic review on measurement properties.

"...Results: Five studies were included, with five unique TCM diagnostic instruments for FD identified. All five diagnostic instruments were of inadequate quality in terms of their development process, implying a shortcoming in their relevance, comprehensibility, and comprehensiveness. Only the criterion validity of was of sufficient quality and had no risk of bias in its validation. ..."
Ho L., Chung V. et al. (2021) Evaluating traditional Chinese medicine diagnostic instruments for functional dyspepsia: systematic review on measurement properties. Integr Med Res. 2021;10(3):100713.   🔗

Acupuncture for Cancer-Related Anorexia: a Review of the Current Evidence.

"PURPOSE OF REVIEW: Loss of appetite/anorexia is extremely common among cancer patients, affecting as many as half of newly diagnosed patients and 70% of patients with advanced disease. Effective management of this disabling symptom of cancer remains a major challenge in the field of oncology. We conducted a systematic review of the current evidence ..."
Liu W., Lopez G. et al. (2021) Acupuncture for Cancer-Related Anorexia: a Review of the Current Evidence. Curr Oncol Rep. 2021;23(7):82.   🔗

Mechanism of Action of Acupuncture in Obesity: A Perspective From the Hypothalamus.

"Obesity is a prevalent metabolic disease caused by an imbalance in food intake and energy expenditure. Although acupuncture is widely used in the treatment of obesity in a clinical setting, its mechanism has not been adequately elucidated. As the key pivot of appetite signals, the hypothalamus receives afferent and efferent signals from the brainstem ..."
Wang L., Yu C. et al. (2021) Mechanism of Action of Acupuncture in Obesity: A Perspective From the Hypothalamus. Front Endocrinol (Lausanne). 2021;12:632324.  🔗

Electro-acupuncture vs. sham electro-acupuncture for chronic severe functional constipation: A systematic review and meta-analysis.

"...RESULTS: The meta-analyses involved 6 studies and 1457 individuals. The pooled results favored the EA group for the increase of complete spontaneous bowel movements (CSBMs) per week in the fourth week (MD = 0.80, P = 0.001) during treatment, and further improved in the eight weeks (MD = 1.25, P < 0.001). During the follow-up period, significant changes in CSBMs per week were seen in the experimental group (MD = 1.38, P = 0.008); the effect decreased in the twelfth week (MD = 0.87, P < 0.001). There was no significant difference in the Bristol stool scale score between the two groups in the fourth week (MD = 0.40, P = 0.08), but significant differences were observed in the eighth week (MD = 0.40, P = 0.03). A significant reduction in patient assessment of constipation quality of life (PAC-QOL) score were observed in the EA group during treatment (SMD = -0.83, P < 0.001). No serious adverse events were reported. ..."
Zhang N., Hou L. et al. (2020) Electro-acupuncture vs. sham electro-acupuncture for chronic severe functional constipation: A systematic review and meta-analysis. Complement Ther Med. 2020;54:102521.  🔗

Acupuncture for ulcerative colitis: a systematic review and meta-analysis of randomized clinical trials.

"...RESULTS: We included 13 RCTs (1030 participants, 515 in the acupuncture group and 515 in the control group). Only one study tested head acupuncture, and the other 12 tested body acupuncture. The treatment duration ranged from 14 to 60 days. Seven trials compared acupuncture alone versus conventional medicine, and six compared acupuncture combined with conventional medicine versus conventional medicine. Acupuncture combined with mesalazine showed better clinical effect (improved clinical symptoms, colonoscopy results and stool examination results) (RR 1.25, 95% CI 1.19 to 1.41; 232 participants; 4 trials; low quality evidence) and better colonoscopy curative effect (RR 1.33, 95% CI 1.04 to 1.71; 108 participants; 2 trials; moderate quality evidence) compared to mesalazine. Acupuncture showed better clinical effect compared to the combination of metronidazole and sulfasalazine (RR 1.21, 95%CI 1.10, 1.34; 318 participants; 3 trials; moderate quality evidence). There was no significant difference in the incidence of adverse events between groups. ..."
Wang X., Zhao N. et al. (2020) Acupuncture for ulcerative colitis: a systematic review and meta-analysis of randomized clinical trials. BMC Complement Med Ther. 2020;20(1):309.   🔗

Complementary, alternative, integrative and dietary therapies for children with Crohn's disease - A systematic review.

"Children with diagnosed inflammatory bowel diseases such as Crohn's disease are faced with the daunting prospect of living with a chronic disease. Besides psychological stress, children are suffering from therapy side-effects; in particular, corticosteroid therapies are problematic in the growth phase. This highlights that there is a need for less aggressive alternative therapies for ..."
Schwermer M., Fetz K. et al. (2020) Complementary, alternative, integrative and dietary therapies for children with Crohn's disease - A systematic review. Complement Ther Med. 2020;52:102493.  🔗

Effects and mechanisms of acupuncture and electroacupuncture for functional dyspepsia: A systematic review.

"...RESULTS: Eight studies were included in this review with a total of 17 items for detecting techniques for mechanistic research. Positive effects of acupuncture and EA were observed in regulating gastric motility, gastric accommodation, mental status, gastrointestinal hormones, and central and autonomic functions while improving dyspeptic symptoms and quality of life. ..."
Guo Y., Wei W. et al. (2020) Effects and mechanisms of acupuncture and electroacupuncture for functional dyspepsia: A systematic review. World J Gastroenterol. 2020;26(19):2440-2457.   🔗

Effects of auriculotherapy on weight and body mass index reduction in patients with overweight or obesity: Systematic review and meta-analysis.

"...RESULTS: The results revealed an association between auriculotherapy and weight reduction (WMD, 1.507; 95% CI, 0.606-2.407; p < 0.000). Auriculotherapy was also significantly associated with BMI reduction (WMD, 0.865; 95% CI, 0.533-1.196; p < 0.004). ..."
Mendonça C., Coelho Dos Santos L. et al. (2020) Effects of auriculotherapy on weight and body mass index reduction in patients with overweight or obesity: Systematic review and meta-analysis. Complement Ther Clin Pract. 2020;38:101069.  🔗

Acupuncture for Adults with Diarrhea-Predominant Irritable Bowel Syndrome or Functional Diarrhea: A Systematic Review and Meta-Analysis.

"Objective. To evaluate the clinical effectiveness and safety of acupuncture therapy in the treatment of diarrhea-predominant irritable bowel syndrome (IBS-D) or functional diarrhea (FD) in adults. Five electronic databases-PubMed, EMBASE, CNKI, VIP, and Wanfang-were searched, respectively, until June 8, 2020. The literature of clinical randomized controlled trials of acupuncture for the treatment of IBS-D or FD ..."
Guo J., Xing X. et al. (2020) Acupuncture for Adults with Diarrhea-Predominant Irritable Bowel Syndrome or Functional Diarrhea: A Systematic Review and Meta-Analysis. Neural Plast. 2020:8892184.  🔗

The Effectiveness of Acupuncture in Management of Functional Constipation: A Systematic Review and Meta-Analysis.

"...Results: The merged data of 28 RCTs with 3525 participants indicated that acupuncture may be efficient for FC by increasing CSBMs ( < 0.00001; MD = 0.84 [95% CI, 0.65 to 1.03];  = 0%) and improving constipation symptoms (=0.03; SMD = -0.4 [95% CI, -0.78 to -0.03];  = 74%), stool formation ( < 0.00001; MD = 0.24 [95% CI, 0.15 to 0.34];  = 0%), quality of life ( < 0.00001;  = 1, MD = -0.33 [95% CI, -0.45 to -0.21]), and responder rates (=0.02; RR = 2.16; [95% CI, 1.1 to 4.24];  = 69%) compared with the effects of sham treatment. No increased risk of adverse events was observed (=0.44; RR = 1.18; [95% CI, 0.77 to 1.81];  = 0%). With regard to medication comparisons, the pooled data indicated that acupuncture was more effective in increasing CSBMs (=0.004; MD = 0.53 [95% CI, 0.17 to 0.88];  = 88%) and improving patients' quality of life ( < 0.00001; SMD = -0.73 [95% CI, -1.02 to -0.44];  = 64%), with high heterogeneity. However, there were no significant differences in responder rate (=0.12; RR = 1.31; [95% CI, 0.94 to 1.82];  = 53%), BSFS (=0.5; MD = 0.17 [95% CI, -0.33 to 0.68];  = 93%), or CSS (=0.05; SMD = -0.62 [95% CI, -1.23 to -0.01];  = 89%). Regarding safety evaluation, acupuncture was safer than medications ( < 0.0001; RR = 0.3; [95% CI, 0.18 to 0.52];  = 30%). ..."
Wang L., Xu M. et al. (2020) The Effectiveness of Acupuncture in Management of Functional Constipation: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med. 2020:6137450.  🔗

Efficacy Comparison of Different Acupuncture Treatments for Functional Dyspepsia: A Systematic Review with Network Meta-Analysis.

"...Results: A total of 35 studies involving 3301 patients and 10 interventions were eligible for this study. NMA results showed that five types of acupuncture (manual acupuncture, acupoint application, moxibustion, acupoint catgut embedding, and warm acupuncture alone) all were superior to prokinetics (itopride, mosapride, and domperidone) and sham acupuncture in terms of improving the symptoms of functional dyspepsia. Specifically, manual acupuncture and electroacupuncture were more effective in improving the MOS 36 Item Short-Form Health Survey (SF-36) compared to itopride and sham acupuncture, and electroacupuncture was the best among the three acupuncture therapies (acupuncture, electroacupuncture, and acupoint catgut embedding). Moxibustion and manual acupuncture were more effective in improving Nepean Dyspepsia Life Quality Index (NDLQI) compared to itopride, domperidone, and sham acupuncture; moxibustion ranks first among the three acupuncture therapies (acupuncture, electroacupuncture, moxibustion). ..."
Zhang J., Liu Y. et al. (2020) Efficacy Comparison of Different Acupuncture Treatments for Functional Dyspepsia: A Systematic Review with Network Meta-Analysis. Evid Based Complement Alternat Med. 2020:3872919.  🔗

Acupuncture for Acute Pancreatitis: A Systematic Review and Meta-analysis.

"...RESULTS: Twelve eligible studies were included finally. The meta-analysis showed that acupuncture plus RT compared with RT alone could significantly improve the total effective rate and gastrointestinal function and reduce the Acute Physiology, Age, Chronic Health Evaluation II score, tumor necrosis factor α count, the time of resuming to diets, and the length of hospital stay. Only 3 of the studies reported adverse events or reactions. ..."
Zhang K., Gao C. et al. (2019) Acupuncture for Acute Pancreatitis: A Systematic Review and Meta-analysis. Pancreas. 2019;48(9):1136-1147.   🔗

Acupuncture in Inflammatory Bowel Disease.

"Scientific research into the effects and mechanisms of acupuncture for gastrointestinal diseases including inflammatory bowel disease has been rapidly growing in the past several decades. In this review, we discuss the history, theory, and methodology of acupuncture and review potentially beneficial mechanisms of action of acupuncture for managing inflammatory bowel disease. Acupuncture has been ..."
Song G., Fiocchi C. et al. (2019) Acupuncture in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2019;25(7):1129-1139.   🔗

The Effectiveness of Acupoint Catgut Embedding Therapy for Abdominal Obesity: A Systematic Review and Meta-Analysis.

"Acupoint catgut embedding is a useful therapy for weight management and widely applied in China. This review aimed to systematically evaluate the effects of acupoint catgut embedding on abdominal obesity. We searched the PubMed, Cochrane-Library, Embase, OVID, MEDLINE, ISI (web of science), Wanfang, VIP, CBM, and CNKI for randomized controlled trials that used acupoint ..."
Sheng J., Jin X. et al. (2019) The Effectiveness of Acupoint Catgut Embedding Therapy for Abdominal Obesity: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med. 2019:9714313.  🔗

Effectiveness of Acupuncture in Treatment of Simple Obesity in Animal Models: A Systematic Review and Meta-Analysis.

"...Results: A total of 108 trials involving 5731 rats were included. Meta-analysis showed that acupuncture had better effect on reducing weight (SMD -2.60, 95%CI: -2.93 to -2.26, p<0.00001) and Lee's index (SMD -2.62, 95%CI:-3.18 to -2.06, p<0.00001) compared with control group. However, the methodological quality of included studies was generally poor. Details of blinding were not reported in most studies. In spite of high heterogeneity being observed on the merged data, sensitivity analysis using the leave-one-out approach, subgroup analysis based on different acupuncture techniques, and rat strains and meta-regression all failed to find the sources of heterogeneity. The asymmetric funnel plot suggested publication bias. Besides, adverse events were not reported in any reports. ..."
Fan X., Yu M. et al. (2019) Effectiveness of Acupuncture in Treatment of Simple Obesity in Animal Models: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med. 2019:5459326.  🔗

Acupuncture plus Chinese Herbal Medicine for Irritable Bowel Syndrome with Diarrhea: A Systematic Review and Meta-Analysis.

"...Results: A total of 21 RCTs related to IBS-D were included into this meta-analysis. Specifically, the pooled results indicated that (1) acupuncture combined with CHM might result in more favorable improvements compared with the control group (relative risk [RR] 1.29; 95% CI 1.24-1.35; P =0.03); (2) the combined method could markedly enhance the clinical efficacy in the meantime of remarkably reducing the scores of abdominal pain (standardized mean difference [SMD] -0.45; 95% CI -0.72, -0.17; P = 0.002), abdominal distention/discomfort (SMD -0.36; 95% CI -0.71, -0.01; P = 0.04), diarrhea (SMD -0.97; 95% CI -1.18, -0.75; P < 0.00001), diet condition (SMD -0.73; 95% CI -0.93, -0.52; P<0.00001), physical strength (SMD -1.25; 95% CI -2.32, -0.19; P = 0.02), and sleep quality (SMD -1.02; 95% CI -1.26, -0.77; P < 0.00001) compared with those in the matched groups treated with western medicine, or western medicine combined with CHM. Additionally, a metaregression analysis was constructed according to the name of prescription, acupuncture type, treatment course and publication year, and subgroup analyses stratified based on the names of prescriptions and acupoints location were also carried out, so as to explore the potential heterogeneities; and (3) IBS-D patients treated with the combined method only developed inconspicuous adverse events; more importantly, the combined treatment had displayed promising long-term efficacy. ..."
Yan J., Miao Z. et al. (2019) Acupuncture plus Chinese Herbal Medicine for Irritable Bowel Syndrome with Diarrhea: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med. 2019:7680963.  🔗

Acupuncture and Related Therapies for Treatment of Postoperative Ileus in Colorectal Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

"Delays in recovery of intestinal function following abdominal surgery are associated with longer hospital stays, increased postoperative complications, and higher costs to the health care system. Studies of acupuncture for postoperative ileus and other postoperative issues have reported improvements. This systematic review and meta-analysis aimed to assess whether acupuncture assisted recovery following surgery for ..."
Liu Y., May B. et al. (2018) Acupuncture and Related Therapies for Treatment of Postoperative Ileus in Colorectal Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evid Based Complement Alternat Med. 2018:3178472.  🔗

Massage Acupuncture, Moxibustion, and Other Forms of Complementary and Alternative Medicine in Inflammatory Bowel Disease.

"Complementary and alternative medicine is frequently used by inflammatory bowel disease (IBD) patients; most common are massage, acupuncture, and moxibustion therapy. Massage therapy is poorly studied in IBD patients; therefore, its benefits remain unknown. Acupuncture and moxibustion therapy have been shown to improve inflammation and symptoms in animal and human studies. However, current clinical ..."
Stein Daniel J.(2017) Massage Acupuncture, Moxibustion, and Other Forms of Complementary and Alternative Medicine in Inflammatory Bowel Disease. Gastroenterol Clin North Am. 2017;46(4):875-880.   🔗